Biochemistry

12 notes

Notes 12

  • Vitamins

    Vitamin A supports retinal function and normal epithelial differentiation. Clinical correlation: Vitamin A deficiency may affect oral and respiratory epithelium as well as vision.

    Biochemistry
  • Cholestrol

    HDL accepts cholesterol from peripheral cells. LCAT esterifies cholesterol, helping retain it within HDL particles for transport toward the liver and other pathways of elimination.

    Biochemistry
  • Fats

    True Essential Fatty Acids (Must be obtained from diet): ◦ Linoleic acid (Omega-6) ◦ alpha-Linolenic acid (Omega-3).

    Biochemistry
  • Carbs

    Non-Reducing Sugar: ◦ Sucrose (Table sugar — composed of Glucose + Fructose linked by an alpha-1,2-glycosidic bond).

    Biochemistry
  • Proteins

    Essential amino acids cannot be synthesized in sufficient amounts by the body and must be supplied through the diet.

    Biochemistry
  • Glycolysis

    Glycolysis converts glucose into pyruvate in the cytoplasm. It can generate ATP without directly requiring oxygen, although the fate of pyruvate depends on cellular conditions.

    Biochemistry
  • Collagen

    Collagen is a major structural protein of connective tissue, bone, skin, tendons, ligaments and the periodontal supporting tissues.

    Biochemistry
  • Glycogen

    Glycogen storage diseases (GSDs) result from defects in enzymes responsible for glycogen synthesis or breakdown. They commonly affect the liver, skeletal muscle or both.

    Biochemistry
  • Lysosomes

    Lysosomal storage diseases result from defects in lysosomal enzymes, activator proteins or transport mechanisms. Undegraded substrates accumulate in lysosomes and damage tissues.

    Biochemistry
  • Nutrition

    Fat is the most energy-dense macronutrient. Typical adult dietary patterns often derive approximately 45–65% of energy from carbohydrates, 20–35% from fats and 10–35% from protein.

    Biochemistry
  • Last Day Revision

    Night blindness, xerophthalmia, Bitot spots. Beriberi, Wernicke–Korsakoff; TPP-dependent enzymes. Neuropathy, seizures, sideroblastic anemia; isoniazid association.

    Biochemistry