Eye

AnatomyUpdated 1 min read
On this page 6 sections

Extraocular muscles

Rule: LR6 – SO4 – Rest3

NerveMuscle
CN VI (abducens)Lateral rectus
CN IV (trochlear)Superior oblique
CN III (oculomotor)Remaining four recti and inferior oblique; also levator palpebrae superioris

Mnemonic: LR6, SO4, all the rest 3.

CN Palsies Table

CN PalsyPresentation
CN IIIPtosis + dilated pupil + eye down-and-out
CN IVImpaired downward gaze in adduction; head tilt opposite side
CN VICannot abduct eye (medially directed)
  • Vertical diplopia = CN IV or CN III.
  • 4th nerve palsy = diplopia on seeing down (vertical).
  • 3rd nerve palsy = diplopia seeing down + right/left (horizontal).
  • 6th nerve palsy = diplopia seeing right or left (horizontal).

Pupil Abnormalities — FCPS High-Yield Notes

Quick reference table

FindingMost likely diagnosis
Ptosis + mydriasis ± diplopiaCN III palsy
Ptosis + miosisHorner syndrome
Light reflex absent, accommodation preservedArgyll–Robertson pupil
Dilated pupil with poor light response, tonic near responseHolmes–Adie pupil
Pinpoint pupils + respiratory depressionOpioid toxicity
Bilateral pinpoint pupilsConsider pontine hemorrhage or drugs
Anisocoria greater in bright lightLarger pupil is abnormal
Anisocoria greater in darknessSmaller pupil is abnormal

Horner syndrome

  • Ptosis
  • Anhidrosis
  • Miosis

Caused by interruption of the sympathetic pathway. Possible causes include a Pancoast tumor, brainstem/spinal cord lesions, or carotid artery dissection. Facial flushing may occur.

Figure: Horner syndrome

CN III palsy

Figure: CN III palsy
  • Ptosis
  • Eye typically “down and out”
  • Diplopia
  • Possible mydriasis if parasympathetic fibres are involved

Argyll–Robertson pupil

Figure: Argyll–Robertson pupil
  • Accommodation response preserved
  • Light reflex absent or markedly impaired
  • Classically associated with neurosyphilis
  • Often bilateral, small and irregular pupils