Face

EmbryologyUpdated 2 min read
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FACE AND PALATE DEVELOPMENT

Development of the Face — Weeks 4–10

The face develops from five main prominences surrounding the primitive mouth (stomodeum).

ProminenceMajor contribution
Frontonasal prominenceForehead and bridge of nose
Medial nasal prominencesPhiltrum of upper lip, premaxillary region and primary palate
Lateral nasal prominencesAlae of nose
Maxillary prominencesLateral upper lip, cheeks and much of the maxilla
Mandibular prominencesLower lip, chin and mandible

Important fusion events

  • The two medial nasal prominences merge to form the intermaxillary segment.
  • The intermaxillary segment contributes to the philtrum, premaxillary region and primary palate.
  • Maxillary prominences merge with the medial nasal prominences to form the upper lip.
  • Mandibular prominences merge in the midline to form the lower jaw and lower lip.

Development of the Palate

The palate develops from the primary palate and secondary palate.

FeaturePrimary palateSecondary palate
OriginIntermaxillary segmentPalatal shelves from maxillary prominences
PositionAnterior to incisive foramenPosterior to incisive foramen
Dental relevanceAssociated with premaxillary regionForms most of the hard and soft palate

Secondary palate formation

  1. Palatal shelves develop from the maxillary prominences.
  2. Initially, the shelves lie vertically beside the tongue.
  3. They elevate into a horizontal position above the tongue.
  4. The shelves grow toward one another and fuse in the midline.
  5. Fusion with the primary palate and nasal septum completes separation of the oral and nasal cavities.

Cleft palate

Failure of palatal shelf elevation, growth or fusion can produce cleft palate.

MCQ tip: Primary palate = intermaxillary segment; secondary palate = palatal shelves.

Development of the Tongue

The tongue develops from multiple pharyngeal arches.

RegionEmbryological originSensory supply
Anterior two-thirdsMainly first archGeneral sensation: lingual nerve (V3); taste: chorda tympani (VII)
Posterior one-thirdMainly third archGlossopharyngeal nerve (IX), for general sensation and taste
Epiglottic regionFourth arch contributionInternal laryngeal branch of superior laryngeal nerve (X)
Tongue musclesOccipital somitesMainly hypoglossal nerve (XII)

Important exception: Palatoglossus is supplied by the vagus nerve through the pharyngeal plexus.